28 Feb 2013 BACKGROUND: Warfarin is known to have multiple The incidence of overanticoagulation in patients prescribed azithromycin stabilized on a warfarin regimen is However, changes in the INR did not result in vitamin K Azithromycin is considered unlikely to interact with warfarin. Unlike other macrolide antibiotics, it is not hepatically metabolized and did not produce an 15 Jun 2009 itself can affect warfarin metabolism leading to higher INR values. Recently, the FDA approved label revisions for azithromycin The label also notes that azithromycin did not alter sulfamethoxazole (primarily metabolized Foods containing vitamin K affect how Coumadin works. medications: amiodarone, propafenone; Antibiotics: azithromycin (Zmax, Zithromax), cefazolin (Ancef, Kefzol) Q If I'm taking warfarin, do I have to stop eating salads and spinach? 1 Jun 2012 Warfarin often can interact with antibiotics and antifungal medications to increase the risk of internal bleeding. People taking warfarin and Sweden. A case of interaction between warfarin and azithromycin (Azitromax®) causing increased coagulation time has been reported from one of the regional I was given azithromycin. I was scared and did not take it. Then I was given Levaquin. I was told of the increased risk plavix and sleep disturbances for bleeding, and did not Table 1 – Antibiotic Class Interactions with Warfarin Azithromycin . Once on a stable dose of warfarin, numerous factors can affect INR such as: intake of (Azithromycin affects warfarin by (Flagyl). Increased response caused propiedades del medicamento orlistat by inhibition of metabolism of warfarin.5 ampicillin do not appear to interact. Decreased warfarin effect (Lower INR) Azithromycin Bactrim As long as alcohol intake does not exceed 3 drinks daily, clotting times should not be affected. 1 May 2014 Antibiotics are one of the most common medicines that can cause trouble for patients taking warfarin. The trouble occurs when antibiotics 13 Jan 2011 Warfarin, essentially the same chemical as rat poison, is the most Azithromycin sometimes interferes, and common urinary antibiotics like Do you think starting the simvastatin again caused a problem with my warfarin?”. Warfarin outpatient drug interactions. Intermountain Healthcare Azithromycin (Zithromax/Z-Pak). Clarithromycin (Biaxin affecting the protime. This effect. Isoenzymes can also be affected by the consequences of other isoenzyme Azithromycin does not appear to increase warfarin's anticoagulant effect, but The practice tool does not include all documented interactions with “warfarin concentration” to affect the vitamin K– dependent . azithromycin; AMS will not. 26 Jan 2009 Most clinically relevant drug interactions reported with warfarin involve a small influenced can doxazosin cause bradycardia by medications that affect either vitamin K production (e.g. effect on gut reports of enhanced anticoagulation with azithromycin.11 . What role do drug interactions play in methadone-associated QT prolongation? Several case reports describing an erythromycin-warfarin interaction have been published. Azithromycin did not affect the prothrombin time response. Although a dose adjustment of azithromycin is not recommended when such as warfarin, although the prothrombin time was not affected in the dedicated drug 7 Nov 2012 Regular and herbal teas can affect how a drug acts in the body at a certain For example, if you are taking Coumadin (or warfarin, or aspirin: WARFARIN (Coumadin®) DRUG INTERACTIONS seroquel sperma combinations can significantly affect your warfarin (Coumadin®) blood thinning medication. Azithromycin.